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Riboflavin is also essential for the metabolism of homocysteine, as a cofactor for methylenetetrahydrofolate reductase (MTHFR) and methionine synthase reductase (MTRR) (11)
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Both have strong safety profiles
Although not a direct drug-drug interaction, increased GH/IGF-1 levels may raise blood glucose
It did also strike me as strange that a person can experience both painless footdrop requiring over-lifting from the knee to avoid tripping and it's total opposite- stiff painful feet and tight heels
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