Within the affected group 17 were diagnosed with Stage 1 Konzo, 7 with Stage 2 konzo and 5 with Stage 3 konzo, however proteomic analysis on the discovery cohort were not segregated based on stage of the disease
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REFERENCES Once-Weekly Semaglutide in Adults with Overweight or Obesity , New England Journal of Medicine, 2021 Efficacy and safety of a novel dual GIP and GLP-1 receptor agonist tirzepatide in patients with type 2 diabetes (SURPASS-1): a double-blind, randomised, phase 3 trial The Lancet, 2021 Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension , Diabetes, Obesity & Metabolism, 2022 Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity: The STEP 4 Randomized Clinical Trial , JAMA, 2021 Changes in lean body mass with glucagon-like peptide-1-based therapies and mitigation strategies , Diabetes, Obesity and Metabolism, 2024 Skeletal muscle loss and sarcopenia in obesity pharmacotherapy, Nature Reviews Endocrinology, 2024 Maintaining Muscle Function Across the Lifespan: The State of Science, American Journal of Physical Medicine & Rehabilitation, 2020 Impact of Glucagon-Like Peptide 1 Agonist Deprescription in Type 2 Diabetes in a Real-World Setting: A Propensity Score Matched Cohort Study , Diabetes Therapy, 2024 Ketogenic diets and appetite regulation , Current Opinion in Clinical Nutrition & Metabolic Care, 2021 Association Between Ketosis and Changes in Appetite Markers with Weight Loss Following a Very Low-Energy Diet, Obesity, 2020 Ketogenic Diet Benefits to Weight Loss, Glycemic Control, and Lipid Profiles in Overweight Patients with Type 2 Diabetes Mellitus: A Meta-Analysis of Randomized Controlled Trials , International Journal of Environmental Research and Public Health, 2022 Impact of the ketogenic diet on body fat, muscle mass, and exercise performance: a review , Physical Activity and Nutrition, 2023 This blog is provided for informational purposes only and should not be considered a replacement for professional medical advice, diagnosis, or treatment
27 However, some research, such as that by de Oliveira et al 30 reported that NAC has metabolic benefits, including reduced insulin resistance and increased HDL-C levels
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