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At baseline, they had an average of 4 DSM-5 alcohol use disorder symptoms (consistent with moderate severity), consumed alcohol 20/28 days and 9/28 days with heavy drinking (4+ for women and 5+ for men each day)

Lifestyle modifications include regular exercise (walking for 30 minutes, yoga, playing sports, or doing household activities)

Despite encouraging progress, important questions remain regarding long-term effects, receptor pharmacology, and future applications

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It calls comprehensive cardiovascular, renal and metabolic screening essential before either therapy is initiated

As new GLP-1 medicines advance through clinical trials, it will be crucial to expand our understanding of their antiinflammatory mechanisms in order to optimize therapeutic use