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The liver, which may be under stress, breaks down alcohol

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doi: 10.3389/fendo.2025.1650729 Received 20 June 2025 Accepted 18 September 2025 Published 01 October 2025 Volume 16 - 2025 Edited by Maria Gazouli, National and Kapodistrian University of Athens, Greece Reviewed by Xiaohang Wang, Affiliated Hospital of Yangzhou University, China Junqing Lin, Shanghai Jiao Tong University, China Guangda He, Chinese Academy of Medical Sciences and Peking Union Medical College, China Updates Copyright 2025 Niu, Chen, Wu, Wang, Xu, Yin and Zhao

In a human trial, high-fiber diets improved sleep and even shifted chronotype earlier (toward morningness), potentially by these gut-mediated pathways (Tarta-Arsene et al., 2017

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Signaling and metabolism