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Some researcher communities report using oral or sublingual routes

For example, cystatin C is suitable for the detection of renal impairment in patients with GFRs in the creatinine-blind range, and it is not significantly influenced by muscle mass, age, or ethnicity (117)

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Patients should be instructed to stop tirzepatide immediately and seek urgent medical care if they develop severe, persistent abdominal pain (with or without vomiting) that could indicate pancreatitis