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Therefore, homozygous and heterozygous carriers of the UGT1A3*5 allele required a higher dose of VPA to reach the therapeutic range in plasma (as measured by therapeutic drug monitoring) in the range of 50100 g/mL [72]

However, L-carnitine markedly increased the serum levels of SOD and GSH-Px, and significantly reduced the serum levels of MDA, compared with the mice with cachexia receiving saline, and these effects of L-carnitine were impaired markedly by treatment with etomoxir (Table I)

doi: 10.1001/archopht.125.12.1652 45 WiersingaWM