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A Quick Analogy to Make Sense of It Imagine your body is a busy factory

It is synthesized from three amino acids in two ATP-dependent steps, beginning with the formation of a peptide bond between -glutamate and cysteine by -glutamylcysteine synthetase (GSH1) and the subsequent addition of glycine, catalyzed by glutathione synthetase (GSH2) (Figure 1: GSH biosynthesis) [20]

Flavonoids in cancer therapy:current and future trends

These compounds are being explored for their ability to not only mitigate oxidative damage but also to modulate bone metabolism and offer effective therapeutic strategies for managing osteoporosis and related bone disorders

[DOI] [PMC free article] [PubMed] [Google Scholar] Kauffman FC (2004) Sulfonation in pharmacology and toxicology

The rationale for stacking: each compound targets a different phase or mechanism of tissue repair, producing synergistic results