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They experience lasting changes in appetite control and manage blood sugar better

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Alpha-lipoic acid treatment decreases serum lactate and pyruvate concentrations and improves glucose effectiveness in lean and obese patients with Type 2 diabetes

Evidently cells can tolerate the burden, deliberately allowing low-grade oxidative stress for the cited and many other vital roles including signal transduction, calcium homeostasis, membrane turnover, redox control and genomic stability

Acknowledgements The authors thank Ann-Cathrine Berg and Eva Hammarstrand for their assistance in clinical data collection and Lisbeth Larsson for her assistance in analyzing the IGF-I and IGFBP-3 samples

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