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Design of the novel protraction mechanism of insulin degludec, an ultra-long-acting basal insulin

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Abbreviations DPP-4: Dipeptidylpeptidase-4 GIP: Glucose-dependent insulinotropic polypeptide GLP-1: Glucagon-like peptide-1 HbA1C: Hemoglobin A1C HDL-C: High-density lipoprotein cholesterol LDL-C: Low-density lipoprotein cholesterol T2DM: Type 2 diabetes mellitus References Elrick H, Stimmler L, Hlad CJ, Arai Y

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Simultaneously, the rising global prevalence of obesity, diabetes and associated conditions has fueled growing demand for effective therapeutic solutions

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