Some of the most commonly discussed include: Wegovy, Zepbound, and Saxenda are approved for weight loss
Two protocols dominate the research community
External resources GLP-1 Receptor Agonists: Beyond Glycemic Control (Nature Reviews Endocrinology) Understanding Obesity: Causes, Consequences, and Treatment (The Obesity Society) And if you have made it this far, in case nobody has told you lately, good morning, and in case I do not see you, good afternoon, good evening, and good night
modest improvements in LDL and HDL ratios Liver health: Significant improvements in non-alcoholic fatty liver disease (NAFLD), an increasingly common obesity-related condition Sleep apnea: The SURMOUNT-OSA trial showed tirzepatide reduced sleep apnea severity by up to 63% Joint health: Weight reduction directly reduces mechanical load on hips, knees, and ankles reducing pain and improving mobility Ready to Find Out If GLP-1 Medication Is Right for You
Mutt's laboratory's peptide production funded a great deal of his research activity (Jrnvall, Agerberth, Zasloff)
Rather than jumping to the maximum dose as quickly as the prescribing guidelines allow, consider staying at each dose level for a longer period