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Interestingly, PHGDH also affects tumor biology independently of its effects in serine metabolism, for example, directly interacting with the RNA-binding protein Poly(rC)-binding protein 2 (PCBP2), and inhibiting its proteasomal degradation

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10.1016/j.jare.2020.07.006 74 YounessR

Population pharmacokinetic modelling of busulfan and the influence of body composition in paediatric fanconi anaemia patients