Doctors also prescribe it to those in recovery from substance use disorder or alcohol addiction
A meta-analysis showed that sulfonylurea use is associated with an increased risk of HCC, while GLP-1RAs can lower the risk of HCC (Wang et al., 2024)
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NHS England has advised against prescribing GLP-1 receptor agonists off-label for weight loss, particularly during supply constraints
Dont use any of these alternative medications without consulting your healthcare provider
GLP-1 RAs act by stimulating insulin secretion in a glucose-dependent manner, inhibiting glucagon release, and slowing gastric emptying, which together improve overall metabolic control and reduce appetite (Nathan et al