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scavenging mitochondrial ROS or inhibiting complex III attenuated these effects without affecting Smad signaling, confirming a Smad-independent mitochondrial mechanism [63]

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Elegant studies have provided important and detailed mechanistic evaluation of the pathways and proteins involved in metabolic regulation, documented changes in protein and RNA expression and identified important relationships, mainly at single points in time

doi: 10.7326/0003-4819-141-11-200412070-00035 64