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Hemoglobin A1c (HbA1c) Why it matters: HbA1c reflects your average blood glucose over the prior two to three months and is the single most important baseline marker for anyone starting a GLP-1 agent

The GH/IGF-1 axis promotes muscle protein synthesis and lean body mass gain, enhances lipolysis and fat oxidation (reducing adipose tissue), stimulates bone formation and mineralization, supports immune function, influences cognitive function and mood, improves sleep quality and architecture, enhances skin collagen production and thickness, and modulates glucose and lipid metabolism

SIRT1 modulates various components within the antioxidant system, such as Heme Oxygenase-1(HO-1), glutathione (GSH), catalase (CAT), superoxide dismutase 1(SOD1) and SOD2 through deacetylation of Nrf2 (Zhang et al., 2018

Knowing the guidelines for each helps healthcare providers tailor treatment

Mass spectrometry confirmation of the correct molecular weight is also important

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