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Besides their nutritional function, peptides also fulfil a variety of other physiological roles, including some functions of the immune system, act as neurotransmitters, cell-to-cell signalling, and functions in growth and development

The paper consolidates studies on ferroptosis in OA, offering a comprehensive understanding of its role and the development of innovative therapies targeting this cell death mechanism to improve treatment outcomes for OA patients

This heightens susceptibility to the toxic effects of iron overload, disrupting intestinal mucosal homeostasis and triggering local inflammation and cell death, ultimately precipitating the onset of gut-associated diseases ( 2.2 Iron overload, deficiency, and IBD pathogenesis In the intestinal microenvironment of IBD, iron overload or functional iron deficiency not only serves as a source of oxidative stress but also acts as a critical factor triggering ferroptosis in intestinal epithelial cells

Glutathione directly supports this important function by neutralizing toxins, heavy metals, and free radicals within liver cells

Monitoring helps manage any side effects and ensures the treatments are working effectively

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