However, as medical aesthetic experts, we feel obligated to inform our patients about an important aspect of rapid weight loss that is often overlooked: its impact on facial appearance and skin health
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Discontinuation Rates Treatment Discontinuation Due to Adverse Events: Retatrutide 9mg: 12.2% Retatrutide 12mg: 18.2% Placebo: 4.0% Interestingly, some discontinuations were attributed to "perceived excessive weight loss" participants felt they were losing weight too rapidly or had reached their desired weight and chose to discontinue
Insurance coverage for GLP-1 medications varies widely depending on your plan type, employer, and state regulations
performed a cross-trial analysis using data from clinical trials of GLP-1RAs (ELIXA, LEADER, SUSTAIN-6, EXSCEL, HARMONY, REWIND, PIONEER-6 [59], and AMPLITUDE-O), SGLT2is (CANVAS and CREDENCE), and finerenone (FIDELIO-DKD and FIGARO-DKD) to estimate the effects of the triple combination therapy of GLP-1RA, SGLT2i, and finerenone using the actuarial method [60]
Cell Rep 40(2):111074
