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Physicians are advised to monitor weight, glucose, and overall comfort

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Dosing should always start low and increase gradually

Instead, we always recommend combining weight loss medication with lifestyle habits that help support a healthy weight

Cocaine Only limited clinical evidence is available for GLP-1RAs in cocaine misuse: a small ( N = 13) proof-of-concept trial across 2 days showed that exenatide compared with placebo did not reduce the number of self-administered cocaine infusions 115 , while a case series of 3 individuals with cocaine-use disorder highlighted the feasibility and safety of using the same drug over 6 weeks, although no efficacy measures were reported 116

Pairing these items with a protein or fat can also help slow down blood sugar rising