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This algorithm represents the consensus of the CEG to initiate therapy when echocardiography is not available, but The EPIC trial did not investigate a cutoff for cardiac enlargement by VHS alone ." (Emphasis added.) is not based on evidence So, the CEG admits that their x-ray-only recommendation is not based upon the EPIC trial and is not based upon any other evidence

Furthermore, GHK-Cu has demonstrated neuroprotective properties and can promote the growth of new neurites, potentially enhancing cognitive function and protecting against age-related decline

doi: 10.1161/ATVBAHA.114.303568 152 HeJZhangXWeiYSunXChenYDengJet al

Carroll et al

Research also explores GHK-Cus role in cellular copper homeostasis , examining how the peptides copper-binding properties influence trace-metal bioavailability and the function of intracellular copper-dependent enzymes

doi: 10.1016/j.ultsonch.2024.106856 136