That is a trivial change
Analysis of commercial claims data covering approximately 50 million insured lives found GLP-1 users experienced: 44% fewer major cardiovascular-related hospitalizations 69% improvement in medical spend growth among diabetes-related GLP-1 users over 30 months 37% improvement in medical spend growth among weight-loss GLP-1 users over 18 months Researchers have also observed positive trends related to inflammatory conditions, cardiovascular disease, and other chronic health concerns
Another approach to optimize weight loss including in diabetes involves the use of a combination of a GLP-1 receptor agonist and a long-acting analog of the cell hormone amylin, known as cagrilintide
Key takeaways Semaglutide is the active ingredient in Ozempic, an FDA-approved injection to lower blood sugar in the treatment of Type 2 diabetes and reduce cardiovascular and kidney risk in certain populations
Journal of Clinical Medicine, 14 (3), 812
Its important to know that prior suggestions that the drug might trigger suicidal thoughts [are] not borne out in this very large and diverse population in the U.S. Our study suggests semaglutide can be safe for those with mental health conditions, Volkow says
