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When a Bonferroni correction was applied, levels of 4 metabolites (-GluCys, LA, D-lactate, and Trp) were still significantly different between control and patient groups, while the following metabolites were present at similar levels in both groups: AA, Kyn, D-Ser, Glu, 3-HB, GSH, 5-HT, Thr, and Tyr (Table 2)

16 participants overall is a small sample size

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Accessed online at Van de Loo AJAE, Mackus M, et al

Yes, and the choice of peptide depends on the primary mechanism driving a persons skin concerns