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How retatrutide works differently Retatrutide represents a new class of medication that simultaneously activates three different hormone receptors in the body

Sustained GH elevation therefore carries a theoretical risk of insulin resistance and higher fasting glucose, which is particularly relevant for people with, or at risk of, type 2 diabetes

Receptor desensitization is less of a concern here than intuition might suggest

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Experts dont know exactly why this is, but suggest it may have something to do with hormones

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