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Gastroenterology 128(4 Suppl 1):S121S127

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Yu, L., Wei, J

Topical Copper Peptides Affects surface layers of skin only Limited penetration through skin barrier Localized effect only where applied Good for maintenance, not transformation No systemic anti-aging benefit Available over-the-counter Injectable GHK-Cu Full systemic delivery to all tissues Reaches dermis, follicles, and healing sites Whole-body anti-aging effect More potent collagen stimulation Gene expression modulation (4,000+ genes) Requires medical prescription They are not mutually exclusive

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Nature 505 , 559563 (2014)