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Cardiovascular effects of glucagon-like peptide 1 (GLP-1) receptor agonists

The most widely used GLP-1 AOM is semaglutide

At refrigerator temperatures, lyophilized powder remains stable for several months

Our patients at Ivm : Real-world data from our GLP-1 ID program shows 19.5% average weight loss at 52 weeks

By month four, the vast majority of patients report energy levels equal to or better than baseline

Notably, based on the results from part 1 of the ESSENCE trial, on 15 August 2025, the FDA approved semaglutide 2.4 mg for the treatment of adults with MASH with moderate to advanced liver fibrosis (consistent with stages F2 to F3 fibrosis)