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[DOI] [PMC free article] [PubMed] [Google Scholar] 28.Chang CH, Tsai WC, Lin MS, Hsu YH, Pang JH

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Phase 2 clinical data shows a clean linear dose-response relationship, with each dose tier producing approximately 3 additional percentage points of weight loss

This hypothesis is supported by several studies that have shown supplementation with SAM improves depressive symptoms (104-107)