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In addition, AMPK can attenuate the hepatic inflammatory microenvironment and slow the progression of fibrosis by inhibiting M1 polarization of macrophages and the activation of hepatic stellate cells (HSCs)

Reported intake or a recent injection is the likely cause, since oral supplements, fortified products, and injected B12 are the most common reasons for a high value

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doi: 10.3389/fimmu.2024.1510693 Received 13 October 2024 Accepted 06 December 2024 Published 20 December 2024 Volume 15 - 2024 Edited by Shuo Wang, Shanghai Jiao Tong University, China Reviewed by Ali Sharif, Lahore College for Women University, Pakistan Wenbin Liu, Guangdong Pharmaceutical University, China Updates Copyright 2024 Pareek, Mehlawat, Tripathi, Pareek, Chaudhary, Ratan, Apostolopoulos and Chuturgoon

An LVEF of less than 40% is indicative of systolic heart failure (52)