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If the lack of a period is due to too much estrogen compared to other hormones, as is the case with PCOS or excess weight, then there is the added risk of having abnormal cells develop in the uterus, Dr

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[DOI] [PubMed] [Google Scholar] 112.Siegrist-Kaiser CA, Pauli V, Juge-Aubry CE, Boss O, Pernin A, et al

Furthermore, it has been identified as an early metabolic change and a prominent feature of the disease (Swerdlow, 2018)