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Unlike many peptides it appears stable in both aqueous solution and gastric acid, facilitating study across multiple administration routes

They also enhance intestinal barrier integrity and mitochondrial health

Gull A, Lone AA, Wani NUI (2019) Biotic and abiotic stresses in plants

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These medications may also support joint health and reduce pain by lowering inflammation, potentially useful for conditions like osteoarthritis or autoimmune arthritis

Abbreviations: CCK cholecystokinin DPPIV dipeptidyl dipeptidase IV FXR farnesoid X receptor GI gastrointestinal GIP glucose-dependent insulinotropic peptide GLP-1 glucagonlike peptide-1 GLP-2 glucagonlike peptide-2 HOMA-IR homeostatic model assessment of insulin resistance PYY peptide YY RYGB Roux-en-Y gastric bypass T2DM type 2 diabetes mellitus TGR5 G-proteincoupled bile acid receptor 1 VSG vertical sleeve gastrectomy