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Limitations Despite the strengths of this retrospective cohort study, including its comprehensive five-year follow-up and detailed hormonal profiling, several limitations must be acknowledged

The -SH groups on these residues act as strong nucleophiles, which can conjugate with a variety of molecules, including other glutathione molecules

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In contrast, if HCV RNA is still detectable at week 24, the likelihood of an SVR is virtually nil and treatment can be stopped or continued with the only aim to slow liver disease progression in patients with a severe prognosis, without any hope to eradicate infection (Figure 1A) [18, 22 ]

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Research in mice given 5-amino-1MQ showed a 7% reduction in body mass over 10 days without any changes in food intake, compared to controls