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doi: 10.1210/en.2019-00588

Wexler DJ (2019): Metformin in the treatment of adults with type 2 diabetes mellitus

These medications, which are used primarily for T2D management, have shown beneficial effects on both cardiac and renal diseases

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In humans, most studies do not show a positive effect on the weight reduction facilitated by L-carnitine

Currently, UA-lowering therapies consist of three classes of drugs: XOR inhibitors (allopurinol, febuxostat and topiroxostat), URAT1 transporter inhibitors (probenecid, benzbromarone and dotinurad) and recombinant uricase (pegloticase)