Ramshanker et al
According to the manufacturer, Aquabeam is for treating lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH) by using a high-velocity water stream to ablate and remove tissue from enlarged prostates
Mitra Assemi Betsy AC
RNA sequencing of efferocytic BMDCs revealed the upregulation of the Slc7a11 gene, cystine/glutamate transporter, that regulates intracellular glutamate for extracellular cysteine exchange and is highly expressed in skin-resident DCs
Understanding both PK and PD, helps estimate the exposure levels likely to be efficacious and the exposure levels that might induce side effects in humans
Sensitivity analyses Compared with SGLT2i alone, combination therapy in people 65 years of age was significantly associated with 51%, 33%, 46%, and 45% lower risk of ischemic stroke, MI, 3-point MACE, and 5-point MACE, respectively (See Supplementary Table 6, Supplementary Materials)