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In a comprehensive US administrative database from 2005 to 2008, GLP-1-based treatments, particularly sitagliptin and exenatide, were associated with a significantly increased risk of acute pancreatitis-related hospitalization in adults with T2DM [59], thereby reinforcing prior mechanistic experimental studies and spontaneous reports to the FDA suggesting a potential causal relationship

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This medications offer a stronger appetite control and greater average weight loss but require close medical monitoring and long-term use

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doi: 10.2337/dc19-0578 169 BornerTDe JongheBCHayesMR