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Microdosing, Clinical Trial Challenges (01:18:58) Sponsor: Helix Sleep (01:20:32) Brain Plasticity & Age

If you can find a way to get people to chronically reduce their caloric intake, it sort of makes sense that it might have an effect on aging

Additionally, gut commensals such as Butyricicoccus pullicaecorum , Butyrivibrio fibrisolvens , Ruminococcus bromii , and members of the family Lachnospiraceae also produce sodium butyrate upon fermenting dietary fibers, which inhibits CRC cell proliferation by regulating immune cells such as natural killer cells and macrophages, and causes apoptosis (Xi et al., 2021)

Your provider should evaluate whether you've reached the dose ceiling (2.4mg weekly), whether dietary intake has drifted upward (the medication suppresses appetite but doesn't eliminate it), or whether extending time at your current dose might restart progress

A registered dietitian can help you create a personalized plan for maintaining weight loss after stopping Ozempic