Which GLP-1 agonist is approved for weight loss
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Kondas J, Dioszeghy G, Konder G et al: Plaque excision and dermal graft in the surgical treatment of plastic induration of the penis (Peyronie's disease)
More precisely, for increasing skeletal muscle mass, volume is the key, where volume is define as (weight lifted per repetition, REPS)*(REPS per set)*(SETS)
Interestingly, tirzepatide, a dual-acting GIP/GLP-1 receptor agonist that is now clinically approved for both obesity and T2D, was designed with an amino acid sequence closely resembling that of native GIP, resulting in strong preference for GIPR binding over the GLP-1R
Journal of Molecular Evolution