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Metformin, through the induction of 5' AMP-activated protein kinase and subsequently insulin sensitivity, has been widely used as a therapeutic agent in various conditions, including type 2 diabetes mellitus, PCOS and gestational diabetes (Reference Rice, Elia and Jawad42)

[78] defined the role of platelets in promoting AILI, depending on the action of PAR-4 on LSECs, as speculated by the authors (Fig

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