It is important to note that microglial nodules are not unique to MS, and are also seen in brain trauma, stroke and even normal aging, where they are thought to play a reactive role to minor myelin injury (Kleinberger et al., 2017
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They showed that the depot formulation of leuprolide is safe and effective in the treatment of advanced prostatic cancer, and that the safety and efficacy of this formulation did not differ significantly from those of the daily subcutaneous formulation
It exhibits anti-inflammatory properties that can help decrease inflammation in joints affected by inflammatory conditions such as arthritis
In addition, we noted that both AAV-BDNF (preventive-like administration) and exogenous rBDNF protein (therapeutic-like administration) exerted protective effects in the ALI model