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The G-Site Subunit B of the holo-structure has only GSH bound, which is bound in the extended conformation and forms salt bridges with Arg16, Lys45 and Glu70 from the N-terminal domain of the same chain, and with Asp104 from the C-terminal domain of the other monomer chain

This secretory phenotype is known as the senescence-associated secretory phenotype (SASP)

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The review provides an introduction to the reproductive toxicity of SSRIs from the aspects of male and female germ cell genesis, embryonic development, reproductive system maturation, and environmental contamination, and it briefly describes the potential mechanisms underlying SSRI-induced reproductive toxicity

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To view a copy of this licence, visit About this article Cite this article Cao, J., Zhou, T., Wu, T