Functional capacity for daily activities
It points to meal composition, physical activity, sleep quality, and stress, along with medication adherence and gastric tolerance, as factors that pull individual outcomes apart
Cummings (00:07:45): Yes, indeed, that's a hot area currently in the California Department of State Hospitals
Furthermore, precision medicine shows promise in this field, but more study is needed to discover reliable biomarkers or clinical traits that can predict individual reactions and aid in patient selection
Other potential risks include gallbladder problems (including gallstones), kidney problems (particularly in patients with existing kidney disease who become dehydrated), and hypoglycemia when combined with other diabetes medications
GLP-1 drugs solve this by using receptor agonists (engineered molecules that bind to and activate the same receptor as the natural GLP-1 hormone) but are built to resist DPP-4 and stay active for much longer