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In this study, after 7 days of intraperitoneal injection with IDPN and saline, behavioral testing showed that administration of IDPN induced significant TS-like and stereotypical behavior compared to that of the CON group (Figure 1B)

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Furthermore, catalpol mitigates Cisplatin-induced kidney injury and suppresses the inflammatory response, including reductions in Tumor Necrosis Factor-alpha (TNF-), interleukin-6 (IL-6), IL-1, IL-8, and iNOS, by activating Nrf2 and inhibiting the NF-B signaling pathway (Zhang J

Diabetes Care 48 , 292300 (2025)