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Faster breakdown The enzyme DPP-IV destroys GLP-1 quickly, shortening how long it can work

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A recent meta-analysis of 14 studies [2] has shown that GLP-1RAs, such as liraglutide, semaglutide, and exenatide, cross the blood-brain barrier (BBB) and affect the brain at all levels, from the molecular to the level of neuronal networks