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additional studies to evaluate the differences in adherence to combination therapy with GLP-1RA and SGLT2i compared with SGLT2i monotherapy and how these differences impact outcomes are needed

Human dosing figures circulating in the research community are either human-equivalent-dose extrapolations from mouse protocols or vendor-driven tablet/capsule suggestions with no primary-source backing

Enzymatic assays revealed that compounds 4i and 4e exhibited the best activities against tyrosinase enzyme with IC 50 values of 1.58 and 1.95 M respectively, surpassing that of the positive control kojic acid (IC 50 = 9.3 M)

[DOI] [PubMed] [Google Scholar] 91.Webb C., Twedt D