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Most plans require a documented body mass index (BMI) of 30 or higher, or 27 with obesity-related conditions like hypertension or type 2 diabetes

The label allows shifting the injection day if needed, provided at least 48 hours separate two doses

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Given the clinical concern for hypercoagulability, it is appropriate to recommend the clinician consider testing instead for the relatively common and more pro-thrombotic factor V (F5) Leiden and prothrombin (factor II- F2 ) G202010A mutations

Coverage begins April 2026 under a demonstration project