The preservation of full efficacy, despite lower potency, suggests that the compound effectively engages key activation-relevant residues within the receptor binding cavity, in agreement with predicted computational analyses
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Omholt, K
Targeting metabolic dysfunction and systemic inflammation offers a promising therapeutic approach for improving asthma control in individuals with obesity and T2DM
et al: GLP-1RA and SGLT2i Medications for Type 2 Diabetes and Alzheimer Disease and Related Dementias. JAMA Neurology, April 7, 2025