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The in vitro data is promising, the mechanism is plausible, and clinical formulations are widely available

doi:10.1016/j.heares.2023.108786 Pournajaf S, Baerz MM, Khoshsirat S

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While singly-housed animals may experience stress that impacts metabolism, body weight, and adiposity 65,66,67,68,69 , the singly-housed animals in this study were treated identically (to the best of the experimenters ability) to minimize and equalize stress across all animals and reduce confounding variables

Washing it off prevents continued exposure overnight

REM sleep has been suggested to play an important function in processing and consolidating emotional memory [17]