Thigh injections can be slightly more uncomfortable than abdominal injections for some people because the thigh has more nerve endings near the surface
In this sense, they may be thought of as disease-modifying agents instead of glucose-lowering therapy
ACT 1: What Is Foundayo, and Why Is It Different
A group of researchers, including oncologists and data scientists, from the University of Florida and Indiana University hypothesized that GLP-1s hold promise in oncology due to their ability to lower glucose, adiposity, insulin resistance, and systemic inflammation factors associated with cancer progression, according to a July 2025 paper published in JAMA
Conclusion: If youve noticed changes in your legs after GLP-1 weight loss, youre not alone
Combining medications (GLP-1 or non-GLP-1), hormone support when appropriate, and lifestyle strategies leads to better long-term results than any single solution alone Frequently Asked Questions (FAQs) Are you guaranteed retatrutide in a clinical trial