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Adverse symptoms can first be noted with the CBC test indicating large RBC or macrocytosisa folate and B12 deficiency

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The peptide decreased median healing time of skin ulcers by 45% compared to placebo when applied topically as a 0.03% cream for three months [20]

Conservative dosing, interval monitoring, clear stopping criteria, and documentation rigorous enough that the data contributes to the evidence base rather than just adding another anecdote

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