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Corroborating this, macrophages of AHR-deficient mice generate increased levels of pro-inflammatory signaling molecules after exposure to LPS [131]

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doi: 10.1038/s41591-019-0509-0

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These abnormalities persist even with a reduced metabolic rate, indicating that vulnerability arises mainly from impaired antioxidant defense rather than increased energy demand (110)

Measurement of lipid peroxidation and glutathione levels The organs such as liver, kidney, heart, spleen and testis were quickly removed, weighted and then kept in a plastic bag at 70 C