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Brain Primary target Nervous System Most potent GHRP for pituitary GH release via ghrelin receptor activation Heart Secondary effect Cardiovascular System Cardioprotective effects independent of GH release

2-hydroxynicotinic acid (2-OHNA) inhibits NAPRT by binding to its active site, preventing the conversion of NA to NAD +

No strong data favors either in humans

However, "well-tolerated" does not mean "side-effect-free" for everyone

But not all forms of GHK-Cu are created equal

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