They may result in using medication to ease symptoms beyond prescribed limits
How Semaglutide and Tirzepatide Compare Both semaglutide and tirzepatide are typically administered as once-weekly injections and are used as part of a broader treatment plan that includes lifestyle support and nutritional guidance
It follows that the secondary benefits derived from substantial weight loss, such as improved blood pressure control, glycaemic control and cardiovascular morbidity, are not optimised until the excess adiposity is lost
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In a call with investors after the results were announced, Martin Lange, executive vice president of R&D, chief scientific officer and member of the Management Board for Novo Nordisk, explained that Zepbound performed unusually well on efficacy compared to what has typically been reported in most previous trials of a similar nature. In a phase 3 trial in adults with pre-diabetes and obesity, participants had an average weight reduction of 22.9% on the highest dose of tirzepatide, 2.1% less weight loss than was seen in the CagriSema comparator trial
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