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Mean percent body weight change at 80 weeks, by dose: Retatrutide 4 mg : 19.0% (47.2 lbs) Retatrutide 9 mg : 25.9% (64.4 lbs) Retatrutide 12 mg : 28.3% (70.3 lbs) Placebo : 2.2% (5.5 lbs) Responder rates at the 12 mg dose are the more interesting number for clinicians
Patients with liver problems: The medication should also be used cautiously in patients with liver problems, necessitating regular monitoring of liver function
10.1111/j.2040-1124.2010.00022.x
The brand claims that the supplement may boost natural GLP-1 hormone levels to reduce hunger and cravings, but as @TheCosmeticLane pointed out, theres no requirement for brands like Lemme to prove scientific efficacy before selling their products
It helps regulate blood sugar, slows stomach emptying and contributes to feelings of fullness
Orforglipron showed higher rates of adverse side effects such as nausea, vomiting and other gastrointestinal issues compared with semaglutide
