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Taking it on an empty stomach or as directed by the packaging helps ensure the best possible uptake

doi: 10.1055/s-2004-826160

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However, significant variations in control types (placebo, MET, or intensive lifestyle), concomitant medications, and follow-up windows mean that a robust head-to-head ranking of strategies is still lacking

Another trial found that vitamin B 6 supplementation (20 mg/day of pyridoxine hydrochloride) for three months improved memory, especially long-term memory, in 38 healthy elderly men (70-79 years) compared to 38 men of similar age who received a placebo (118)